Acute dystonic reaction caused by metoclopramide, versus tetanus

Dystonic reactions in children caused by metoclopramide.

Acute dystonic reaction to metoclopramide in patients carrying homozygous cytochrome P450 2D6 genetic polymorphisms.

BACKGROUND Extrapyramidal syndromes (EPS) are clinically relevant side effects of metoclopramide which are often not anticipated. PATIENTS AND METHODS Two patients who received metoclopramide developed an acute dystonic reaction. Symptoms disappeared after biperiden or trihexyphenidyl were given. Molecular analysis of the CYP2D6 gene was performed using a PCR-based method. RESULTS Both pati...

Dystonic reactions to metoclopramide (maxolon).

METOCLOPRAMIDE has been used in the treatment of various gastro-intestinal disorders for over a decade. Dystonic reactions to metoclopramide have been reported previously by Casteels-Van Daele et al (1970) and also Witzel (1968). The symptoms of dystonia appeared in their patients following the administration of metoclopramide in doses exceeding 0.5 mg/kg body weight for longer than a 24-hour p...

IMAGES IN CLINICAL MEDICINE. An Acute Dystonic Reaction after Treatment with Metoclopramide.

Acute Dystonic Reaction Associated with Cefuroxime Axetil in a Child Running Title: Acute Dystonic Reaction

Dystonia is an extrapyramidal motor function disorder characterized by intermittent spasmodic or sustained involuntary muscle contractions of the face, neck, trunk, pelvis and extremities causing repetitive movements and postural abnormalities [1,2]. The abnormal posture may induce significant anxiety and distress for the patient and relatives. In adults, the head and neck muscles are the most ...